P-type Na⁺ transporter

In enzymology, a P-type Na⁺ transporter (EC 7.2.2.3) is an enzyme that catalyzes the chemical reaction

ATP + H₂O + Na⁺_{[side 1]} ${\displaystyle \rightleftharpoons }$ ADP + phosphate + Na⁺_{[side 2]}

The 3 substrates of this enzyme are ATP, H₂O, and Na⁺, whereas its 3 products are ADP, phosphate, and Na⁺.

This enzyme belongs to the family of translocases, specifically those catalysing the translocation of inorganic cations and their chelates. The systematic name of this enzyme class is ATP phosphohydrolase (P-type, Na⁺-exporting).

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• Saier MH Jr (1998). Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya. Advances in Microbial Physiology. Vol. 40. pp. 81–136. doi:10.1016/S0065-2911(08)60130-7. ISBN 9780120277407. PMID 9889977. {{cite book}}: |journal= ignored (help)